Topological and hydraulic metrics-based search space reduction for optimal re-sizing of water distribution networks

Pipe re-sizing of water distribution networks (WDNs) aims at improving the service performance to the required level, while minimizing the cost womens sports bra of replacing pipes in the network.The main challenge comes from the identification of the most effective pipes to re-size from a large number of interacting components.Performing a global

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o-Nitroaryl-bis(5-methylfur-2-yl)methanes as Versatile Synthons for the Synthesis of Nitrogen-Containing Heterocycles

2-Nitroaryldifurylmethanes 1a and 1b, readily available by condensation of 2-nitrobenzaldehyde and 6-nitroveratraldehyde with Bats 2-methylfuran, were transformed into indole, cinnoline and benzothiazine-3,1 derivatives.The reduction of 2-nitroaryldifurylmethanes gave the corresponding anilines 2a,b or indole 3 depending on the reaction conditions.

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